Ki-Nam's paper in ART

Ki-Nam's manuscript was published in Arthritis Research & Therapy (IF=4.148) on Aug 28, 2019. Ki-Nam and colleagues conducted the first genome-wide analysis of copy number variation (CNV) to identify which structural variations including large duplication and deletion were associated with response to the TNF-α blocker therapy in patients with rheumatoid arthritis (RA). CNV was profiled using fluorescence signals from a genome-wide SNP array. She identified the deletion at 2q14.3 that confers poor efficacy of TNF-α blocker therapy.

Congrats!

==========

​Deletion at 2q14.3 is associated with worse response to TNF-α blockers in patients with rheumatoid arthritis.

Ki-Nam Gu^, So-Young Bang^, Hye-Soon Lee, Youngho Park, Ju-Yeon Kang, Ji-Soong Kim, Bora Nam, Hyun-Seung Yoo, Jung-Min Shin, Yeon-Kyung Lee, Tae-Han Lee, Sehwan Chun, Soo-Kyung Cho, Chan-Bum Choi, Yoon-Kyoung Sung, Tae-Hwan Kim, Jae-Bum Jun, Dae Hyun Yoo, Kwangwoo Kim*, Sang-Cheol Bae2*

Arthritis Res Ther. 28;21:195. doi: 10.1186/s13075-019-1983-y. [August, 2019]