Eunji has successfully conducted a CD4-positive T-cell study to understand how genetic variants shape the disease-specific transcriptomic signatures in CD4-positive T cells in patients with rheumatoid arthritis (RA). This has been her major project over the past two or three years. Her work was accepted for publication in Annal of the Rheumatic Diseases (Ann Rheum Dis; IF=16.102) and online published in January 2021. Congrats!
This study illustrates the advantage of the same-sample inter-omics data analysis on disease-relevant tissues in dissecting the complex transcriptional regulation driven by genome-wide genetic variants. You can find the whole scientific results at http://dx.doi.org/10.1136/annrheumdis-2020-219152 and some story behind her work at https://www.ibric.org/myboard/read.php?Board=hbs_treatise&id=67399&idauthorid=33361.
This research was made possible thank to the active collaboration with Dr. Bong-Jo Kim (at Korea NIH), Prof. Sang-Cheol Bae (Hanyang University Hospital for Rheumatic Diseases), and all the other wonderful collaborators who are well versed in the generation of excellent clinical and omics data.
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